Advances in Research on Regulatory Mechanism of Abnormal MiRNA Expression in Digestive System Diseases
10.3969/j.issn.1008-7125.2020.08.012
- Author:
Yongze CHEN
1
;
Yu ZHOU
1
;
Weiyun WU
1
Author Information
1. Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University
- Publication Type:Journal Article
- Keywords:
Digestive System Diseases;
MicroRNAs;
Regulatory Mechanism
- From:
Chinese Journal of Gastroenterology
2020;25(8):506-509
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA) is a non-coding single strand endogenous RNA, with a length of 20-25 bp. It regulates the transcription and translation of target mRNA by binding to its 3' untranslated regions (UTR). Abnormal expression of miRNA plays an important role in the occurrence and development of digestive system diseases. Clarifying the regulatory mechanism of miRNA will be of great help for early diagnosis and treatment of diseases. This article reviewed the advances in research on regulatory mechanism of abnormal miRNA expression in digestive system diseases.
