Role of Small Intestinal Bacterial Overgrowth in Pathogenesis of Irritable Bowel Syndrome
10.3969/j.issn.1008-7125.2020.09.007
- Author:
Xin PAN
1
;
Qian LIU
1
;
Xiaolan ZHANG
1
Author Information
1. Department of Gastroenterology, The Second Hospital of Hebei Medical University
- Publication Type:Journal Article
- Keywords:
Gut Microbiota;
Irritable Bowel Syndrome;
Small Intestinal Bacterial Overgrowth;
Therapy
- From:
Chinese Journal of Gastroenterology
2020;25(9):552-555
- CountryChina
- Language:Chinese
-
Abstract:
Irritable bowel syndrome (IBS) is a common defecation related functional disease, presented as recurrent abdominal discomfort accompanied by a change in bowel habits. The pathogenesis of IBS is still unclear. Several factors have been identified as the etiological factors, such as altered gastrointestinal motility, visceral hypersensitivity, intestinal infection, and immunological activation, etc. Now more and more researches suggest that small intestinal bacterial overgrowth (SIBO) might be one of the pathogenic factors of IBS. This article reviewed the correlation of IBS with SIBO, the possible mechanism and treatment, so as to provide a reference for clinical diagnosis and treatment of IBS combined with SIBO.
