A Case of Diffuse Cutaneous Mastocytosis in a Newborn.
10.14734/kjp.2014.25.2.105
- Author:
Mi Na PARK
1
;
Geun A KIM
;
Myoung Jae CHEY
;
Gyu Hong SHIM
Author Information
1. Department of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. peddoc@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous mastocytosis;
Diffuse cutaneous mastocytosis;
Newborn
- MeSH:
Anaphylaxis;
Blister;
Erythema;
Female;
Humans;
Infant, Newborn*;
Korea;
Mast Cells;
Mastocytosis;
Mastocytosis, Cutaneous*;
Pruritus
- From:Korean Journal of Perinatology
2014;25(2):105-109
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diffuse cutaneous mastocytosis (DCM) is a rare variant of mast cell disease with widespread erythema and is clinically apparent in early infancy. We report the case of a 1-day-old female neonate who presented with diffuse flush, pruritus, and extensive blistering. DCM was diagnosed by immunohistochemical staining with anti-CD117, which revealed mast cell infiltration. DCM is a severe and heterogeneous cutaneous disease, and is associated with mast cell mediator-related symptoms and risk of anaphylactic shock. We describe this case and provide the first literature review of neonatal onset DCM in Korea.
