Progress in Research on Correlation Between Toll-like Receptors and Barrett's Esophagus
10.3969/j.issn.1008-7125.2020.12.012
- Author:
Ningning YANG
1
;
Shizhu JIN
1
;
Ning LI
1
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University
- Publication Type:Journal Article
- Keywords:
Barrett Esophagus;
Inflammation;
Pathogenesis;
Toll-Like Receptors
- From:
Chinese Journal of Gastroenterology
2020;25(12):764-766
- CountryChina
- Language:Chinese
-
Abstract:
Barrett's esophagus (BE), the only recognizable precancerous lesion of esophageal adenocarcinoma (EAC), is a common disease characterized by abnormal transformation of squamous epithelium into intestinal columnar epithelium. Toll-like receptors (TLRs) are important pattern recognition receptors that play a central role in innate and adaptive immunity. TLRs are involved in the identification of almost all pathogens. In addition, TLRs signaling pathway is important for the occurrence and development of BE. This article reviewed the progress in research on the correlation between TLRs and BE.
