Advances in Study on Pathogenesis and Treatment of Diabetic Gastroparesis
10.3969/j.issn.1008-7125.2020.12.011
- Author:
Haoran XIE
1
;
Xiaoyuan GONG
1
;
Lanting YU
1
;
Qiuyan ZHAO
1
;
Baiwen LI
1
;
Hongyu LIAO
2
Author Information
1. Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University
2. Zhanang County Health Service Center, Xizang Autonomous Region
- Publication Type:Journal Article
- Keywords:
Diabetes Complications;
Diabetes Mellitus;
Gastroparesis;
Pathogenesis;
Therapy
- From:
Chinese Journal of Gastroenterology
2020;25(12):759-763
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic gastroparesis (DGP) is characterized by delayed gastric emptying caused by reduction of gastrointestinal motility. Its clinical manifestations include vomiting, nausea, belching, early satiety, postprandial fullness, and abdominal distention, etc. The mechanism of DGP is still not clear. Depletion of interstitial cells of Cajal, myopathy and neuropathy are considered to be the main pathogenic factors. Gastric prokinetics, gastric electric stimulation and endoscopic therapy are the main treatment options, but the long-term efficacy of these symptomatic treatment is not very satisfactory, which seriously affects patients' quality of life. This article reviewed the advances in study on pathogenesis and treatment of DGP.
