Progress in Research on Epigenetics of Irritable Bowel Syndrome
10.3969/j.issn.1008-7125.2021.02.008
- Author:
Huihui XU
1
;
Lujia DONG
1
;
Huifang LI
1
;
Yujun LUO
1
;
Dechun LIU
1
;
Kaige WANG
2
;
Dechun LIU
3
Author Information
1. College of Clinical Medicine of Henan University of Science and Technology
2. The First Clinical Medical College, Lanzhou University
3. Department of Gastrointestinal Surgery, The First Affiliated Hospital of Henan University of Science and Technology
- Publication Type:Journal Article
- Keywords:
Epigenetics;
Irritable Bowel Syndrome;
Therapy
- From:
Chinese Journal of Gastroenterology
2021;26(2):121-123
- CountryChina
- Language:Chinese
-
Abstract:
Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by abdominal pain and changes in bowel habits. IBS is a multifactorial, stress-sensitive disease. Epigenetic changes include DNA methylation change, histone modification, and differential expressions of microRNA and long non-coding RNA. Explaining the changes in IBS from the perspective of epigenetics could bring new insights for the pathogenesis and treatment of the disease. This article reviewed the progress in research on the epigenetics of IBS.
