Effects of Exosomes and Their Contents on Pathogenesis and Development of Gastric Cancer
10.3969/j.issn.1008-7125.2021.06.011
- Author:
Ziqi ZHAO
1
;
Kunming NI
1
;
Weiwei FU
1
;
Shigang DING
1
Author Information
1. Department of Gastroenterology, Peking University Third Hospital
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Exosomes;
Mechanisms;
Stomach Neoplasms;
Therapy
- From:
Chinese Journal of Gastroenterology
2021;26(6):373-377
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is a malignant tumor with worldwide high incidence and threatening the human health severely. It is a disease induced by multiple factors. Exosomes play an important role in the pathogenesis and development of many malignant tumors including gastric cancer. Exosomes can transport specific contents to regulate local and distant cell communications, and are able to promote or inhibit the development of gastric cancer through regulating the growth and proliferation of tumor cells, relevant immune function and angiogenesis of tumors. This article reviewed the effects of exosomes and their contents on the pathogenesis and development of gastric cancer.
