Correlation of Platelet, D-Dimer and Procalcitonin With Acute Cholangitis
10.3969/j.issn.1008-7125.2021.06.003
- Author:
Shangfei ZHAO
1
;
Na JIANG
2
;
Mingquan SONG
3
Author Information
1. Department of Gastroenterology, Qingdao Eighth People's Hospital
2. Center of Digestive Endoscopy, Qingdao Eighth People's Hospital
3. Department of Gastroenterology, The Affiliated Hospital of Qingdao University
- Publication Type:Journal Article
- Keywords:
Acute Cholangitis;
Blood Platelets;
D-Dimer;
Diagnosis;
Procalcitonin
- From:
Chinese Journal of Gastroenterology
2021;26(6):332-336
- CountryChina
- Language:Chinese
-
Abstract:
Background: Early diagnosis and severity assessment of acute cholangitis is an important means to improve the prognosis of acute cholangitis. Aims: To investigate the clinical value of serum platelet (PLT), D-dimer (D-D) and procalcitonin (PCT) for severity assessment in patients with acute cholangitis. Methods: A total of 96 patients with acute cholangitis were enrolled, and were divided into mild group (n=40), moderate group (n=32), severe group (n=24). Levels of serum PLT, D-D and PCT were compared among the three groups. ROC curve was used to verify the predictive value for the severity assessment of acute cholangitis. Results: The serum levels of D-D and PCT increased with the increase of severity of acute cholangitis, and the differences were statistically significant (P<0.05). The serum level of PLT decreased with the increase of severity of acute cholangitis, and the difference was statistically significant (P<0.05). Correlation analysis showed that serum levels of D-D, PCT was positively correlated with severity of acute cholangitis, while serum level of PLT was negatively correlated with severity of acute cholangitis (P<0.05). When the cut-off values were 135.6×10
