Stem Cell Therapy for the Treatment of Hip Osteonecrosis: A 30-Year Review of Progress.
- Author:
Philippe HERNIGOU
1
;
Matthieu TROUSSELIER
;
Francois ROUBINEAU
;
Charlie BOUTHORS
;
Nathalie CHEVALLIER
;
Helene ROUARD
;
Charles Henri FLOUZAT-LACHANIETTE
Author Information
- Publication Type:Review
- Keywords: Hip; Osteonecrosis; Cell therapy; Mesenchymal stromal cells; Tissue engineering
- MeSH: *Cell- and Tissue-Based Therapy; Femur Head/*surgery; Femur Head Necrosis/*surgery; Humans; *Mesenchymal Stem Cell Transplantation; *Tissue Engineering
- From:Clinics in Orthopedic Surgery 2016;8(1):1-8
- CountryRepublic of Korea
- Language:English
- Abstract: Avascular necrosis of the femoral head is caused by a multitude of etiologic factors and is associated with collapse with a risk of hip arthroplasty in younger populations. A focus on early disease management with the use of stem cells was proposed as early as 1985 by the senior author (PH). We undertook a systematic review of the medical literature to examine the progress in cell therapy during the last 30 years for the treatment of early stage osteonecrosis.
