Relationship Between Gastrointestinal Diseases and Migraine Without Aura: A Cross-sectional Study
10.3969/j.issn.1008-7125.2021.07.007
- Author:
Xiaosa JIANG
1
;
Qian YANG
1
;
Xiaohui ZHANG
1
;
Yujie HAO
1
;
Na LIU
1
;
Jinhai WANG
1
;
Wanhai QIAO
2
;
Yuli CHEN
3
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University
2. Department of Gastroenterology, Huangling People's Hospital
3. Department of Gastroenterology, Xi'an Jiren Hospital
- Publication Type:Journal Article
- Keywords:
Cross-Sectional Studies;
Functional Dyspepsia;
Gastroesophageal Reflux Disease;
Irritable Bowel Syndrome;
Migraine Without Aura
- From:
Chinese Journal of Gastroenterology
2021;26(7):418-423
- CountryChina
- Language:Chinese
-
Abstract:
Background: Previous studies have found that patients with gastrointestinal diseases have a higher incidence of headache, while migraine patients are often accompanied by gastrointestinal symptoms. Understanding the relationship between diseases can provide new ideas for the study of its mechanism. Aims: To explore the co-occurrence and related risk factors of gastroesophageal reflux disease (GERD), functional dyspepsia (FD), irritable bowel syndrome (IBS) and migraine without aura (MWoA). Methods: A total of 2 696 adult rural residents in Shaanxi Province were investigated by random stratified sampling. MWoA, GERD, FD and IBS were diagnosed based on ICHD-IIIβ, Montreal classification and Rome , respectively. The prevalence of the single disease and overlapping prevalence of MWoA were calculated. The prevalence rates of GERD, FD and IBS between MWoA group and non-MWoA group were compared, and the disease-related risk factors were analyzed. Results: In this study, a total of 2 423 valid questionnaires were collected. The prevalence rates of GERD, FD and IBS were 12.5%, 15.6% and 6.9%, respectively, and the prevalence rate of MWoA was 8.8%. The prevalence rates of GERD (30.5% vs. 10.7%), FD (37.1% vs. 13.5%) and IBS (27.2% vs. 4.9%) in MWoA group were all higher than those in non-MWoA group (P all < 0.001). Multivariate analysis showed that female, hypertension, chronic motor system diseases were positively correlated with GERD, FD, IBS and MWoA. Conclusions: There is a certain association between GERD, FD, IBS and MWoA.
