Research Progress of NGAL in Inflammatory Bowel Disease

Author: Wenxuan CHEN ¹ ; Li GENG ¹ ; Dandan WANG ¹ ; Muhan ZHANG ¹ ; Zhe ZHANG ¹ ; Baisui FENG ¹
Author Information

1. Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University
Publication Type:Journal Article
Keywords: Inflammatory Bowel Disease; Intestinal Epithelial Cell Barrier; Intestinal Flora; Intestinal Homeostasis; Neutrophil Gelatinase-Associated Lipocalin
From:Chinese Journal of Gastroenterology 2021;26(8):494-497
CountryChina
Language:Chinese
Abstract: Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disease of gastrointestinal tract, including Crohn's disease and ulcerative colitis. The exact etiology and pathogenesis of IBD are still not clear. Neutrophil gelatinase-associated lipocalin (NGAL) plays an important role in regulating intestinal immunity, maintaining intestinal epithelial cell barrier, and coordinating the composition of intestinal flora. In addition, NGAL is useful for helping the clinical testing of IBD. This article reviewed the research progress of NGAL in IBD.