Role of Long Noncoding RNA H19 in Intestinal Mucosal Barrier Function
10.3969/j.issn.1008-7125.2021.10.011
- Author:
Xuejun LIANG
1
;
Lei YE
1
;
Fangyu WANG
1
Author Information
1. Department of Gastroenterology, Jinling Hospital, Southern Medical University
- Publication Type:Journal Article
- Keywords:
Colorectal Neoplasms;
Intestinal Inflammation;
Intestinal Mucosal Barrier;
Long Noncoding RNA H19
- From:
Chinese Journal of Gastroenterology
2021;26(10):636-640
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNA (lncRNA) are defined as noncoding RNA with a length of more than 200 nucleotides, which can regulate a variety of cellular processes. LncRNA H19 is widely involved in the pathophysiological process of intestinal inflammation and intestinal cancer by regulating the function of intestinal mucosal barrier. This article reviewed the effect of lncRNA H19 on intestinal mucosal barrier under different intestinal states and inflammation-cancer related signaling pathway.
