Predictive Value of Systemic Immune⁃inflammation Index for Severe Acute Pancreatitis

Xiamin TU; Yaoyao LI; Yuanzhi Wang; Yang Pan; Jie LI; Xin Gao; Guotao LU; Weiming Xiao; Xiamin TU; Yaoyao LI; Yuanzhi Wang; Xiaoyan Luo; Yang Pan; Jie LI; Xin Gao; Guotao LU; Weiming Xiao; Xiaoyan Luo

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Predictive Value of Systemic Immune⁃inflammation Index for Severe Acute Pancreatitis

Author: Xiamin TU ¹ ; Yaoyao LI ¹ ; Yuanzhi WANG ¹ ; Yang PAN ¹ ; Jie LI ¹ ; Xin GAO ¹ ; Guotao LU ¹ ; Weiming XIAO ¹ ; Xiamin TU ² ; Yaoyao LI ² ; Yuanzhi WANG ² ; Xiaoyan LUO ² ; Yang PAN ² ; Jie LI ² ; Xin GAO ² ; Guotao LU ² ; Weiming XIAO ² ; Xiaoyan LUO ³
Author Information

1. Department of Gastroenterology, Pancreatic Center, Affiliated Hospital of Yangzhou University
2. Yangzhou Key Laboratory of Pancreas in Jiangsu Province
3. Dalian Medical University
Publication Type:Journal Article
Keywords: Acute Pancreatitis; ROC Curve; Systemic Immune‑Inflammation Index
From: Chinese Journal of Gastroenterology 2022;27(2):92-96
CountryChina
Language:Chinese
Abstract: Background: The systemic immune inflammation index (SII) is a reproducible biomarker of inflammatory process. Aims: To explore the predictive value of SII for severe acute pancreatitis (SAP). Methods: A total of 406 patients with acute pancreatitis (AP) from Jan. 2013 to Dec. 2020 at Affiliated Hospital of Yangzhou University were collected, and were divided into SAP group and non SAP group. ROC curve was drawn to evaluate the value of SII, NLR, PLR, CAR for predicting SAP. Results: Compared with non‑SAP group, SII, NLR, PLR, CAR were significantly increased in SAP group (P<0.05). When the best cut‑off value was 1 705.83, AUC of SII for predicting SAP was 0.754, the sensitivity was 75.47%, and the specificity was 69.12%. AUC of SII for predicting SAP was higher than that of PLR, CAR (Z=2.647, P=0.007; Z= 2.616, P=0.008), while no significant difference was found between SII and NLR (P>0.05). And no significant difference in AUC was found between PLR and CAR (P>0.05). Conclusions: SII is a good new hematological index that can be used to predict the severity of AP, its predictive ability is similar to NLR, better than PLR and CAR.