Progress in Research on Glutamine Metabolism in Energy Metabolism of Gastric Cancer
10.3969/j.issn.1008-7125.2022.06.005
- Author:
Xinrong WU
1
;
Yunrong WANG
1
;
Wenqi SUN
1
;
Min CHEN
1
Author Information
1. Department of Gastroenterology, Nanjing Drum Tower Hospital, the Affiliated Hospital, Nanjing University Medical School
- Publication Type:Journal Article
- Keywords:
Amino Acid Transporters;
Energy Metabolism;
Glutaminase;
Glutamine;
Non⁃Coding RNAs;
Stomach Neoplasms
- From:
Chinese Journal of Gastroenterology
2022;27(6):376-380
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is one of the most common malignant tumors of digestive system. Due to lack of early diagnosis methods, the mortality rate of gastric cancer is relatively high. For meeting their own needs, the tumor cells can reprogram their metabolism, and glutamine metabolism plays an important role in tumor cell growth and proliferation. Therefore, it needs to elucidate the new potential molecular mechanisms of gastric cancer and to discover the potential biomarkers related to glutamine metabolism, so as to provide new targets and schemes for the diagnosis and treatment of gastric cancer. This article reviewed the progress in research on glutamine metabolism in energy metabolism of gastric cancer.
