Association Between a Close Distal Resection Margin and Recurrence After a Sphincter-Saving Resection for T3 Mid- or Low-Rectal Cancer Without Radiotherapy.
- Author:
Jae Woong HAN
1
;
Min Jae LEE
;
Ha Kyung PARK
;
Jae Ho SHIN
;
Min Sung AN
;
Tae Kwun HA
;
Kwang Hee KIM
;
Ki Beom BAE
;
Tae Hyun KIM
;
Chang Soo CHOI
;
Sang Hoon OH
;
Min Kyung OH
;
Mi Seon KANG
;
Kwan Hee HONG
Author Information
- Publication Type:Original Article
- Keywords: Rectal neoplasms; Distal resection margin; Recurrence
- MeSH: Humans; Quality of Life; Radiotherapy*; Rectal Neoplasms; Recurrence*; Retrospective Studies; Survival Rate
- From:Annals of Coloproctology 2013;29(6):231-237
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: To maintain the patient's quality of life, surgeons strive to preserve the sphincter during rectal cancer surgery. This study evaluated the oncologic safety of a sphincter-saving resection with a distal resection margin (DRM) <1 cm without radiotherapy in T3, mid- or low-rectal cancer. METHODS: This retrospective study enrolled 327 patients who underwent a sphincter-saving resection for proven T3 rectal cancer located <10 cm from the anal verge and without radiotherapy between January 1995 and December 2011. The oncologic outcomes included the 5-year cancer-specific survival, the local recurrence, and the systemic recurrence rates. RESULTS: In groups A (DRM < or =1 cm) and B (DRM >1 cm), the 5-year cancer-specific survival rates were 81.57% and 80.03% (P = 0.8543), the 5-year local recurrence rates were 6.69% and 9.52% (P = 0.3981), and the 5-year systemic recurrence rates were 19.46% and 23.11% (P = 0.5750), respectively. CONCLUSION: This study showed that the close DRM itself should not be a contraindication for a sphincter-saving resection for T3 mid- or low-rectal cancer without radiotherapy. However, a prospective randomized controlled trial including the effect of adjuvant therapy will be needed.
