Correlation Between Nutritional Risk and Clinical and Endoscopic Features in Crohn's Disease Patients Treated With Biological Agents
10.3969/j.issn.1008-7125.2023.01.007
- Author:
Shuang ZHANG
1
;
Yun YE
1
;
Weiwei WANG
1
;
Pengyue ZHANG
2
;
Qiao MEI
2
;
Naizhong HU
2
Author Information
1. Department of Gastroenterology, the Third People's Hospital of Bengbu
2. Department of Gastroenterology, the First Affiliated Hospital of Anhui Medical University
- Publication Type:Journal Article
- Keywords:
Biological Agents;
Crohn Disease;
Nutritional Risk;
Rutgeerts Score;
SES⁃CD Score
- From:
Chinese Journal of Gastroenterology
2023;28(1):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Background: The widespread use of biological agents in recent years can improve the nutritional status of partial patients with Crohn's disease (CD) and change the course of the disease. Aims: To investigate the correlation between the nutritional risk and clinical and endoscopic features in CD patients treated with biological agents. Methods: Sixty⁃eight CD patients treated with biological agents from June 2021 to June 2022 at the First Affiliated Hospital of Anhui Medical University were enrolled. Nutritional risk screening was conducted by nutritional risk screening 2002 (NRS2002), and its correlation with clinical and endoscopic features was analyzed. Results: In 68 CD patients treated with biological agents, incidence of nutritional risk was 66.2%. There was statistically significant difference in incidence of nutritional risk in patients with different disease behaviors, SES⁃CD score and postoperative Rutgeerts score (all P<0.05). The incidence of nutritional risk was not correlated with age, lesion location, perianal lesion, CDAI score, and the interval between CD diagnosis and the use of biological agents (all P>0.05). Conclusions: The incidence of nutritional risk is high in CD patients treated with biological agents, and is correlated with CD disease behavior, SES ⁃ CD score, and postoperative Rutgeerts score.
