Progress of research on gut flora and inflammatory bowel disease accompanied with spondyloarthritis
10.3969/j.issn.1008-7125.2023.04.007
- Author:
Zhangni LEI
1
;
Mofan XIAO
1
;
Yuling CHEN
1
;
Haichen LI
1
;
Yingchao LI
1
Author Information
1. Department of Gastroenterology, the First Affiliated Hospital of Xi, an Jiaotong University
- Publication Type:Journal Article
- Keywords:
Gut Flora;
Gut‑Joint Axis;
Inflammatory Bowel Disease;
Spondyloarthritis
- From:
Chinese Journal of Gastroenterology
2023;28(4):249-253
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic non ‑ specific intestinal inflammatory disease. Spondyloarthritis (SpA) is a chronic inflammatory disease that occurs in the axial skeleton and surrounding joints, and is one of the most common extraintestinal manifestations of IBD. The main pathophysiologic mechanism of IBD accompanied with SpA involves the "gut‑joint axis" hypothesis, and dysbiosis of gut flora plays a key role in explaining the pathologic connection of the "gut‑joint axis" in patients with IBD accompanied with SpA. This article reviewed the progress of research on gut flora and IBD accompanied with SpA.
