The Role of Post-Translational Modifications of Cav3. 2 in Neuropathic Pain
10.13865/j.cnki.cjbmb.2022.10.1331
- Author:
Xue-Ming CAO
1
;
Dong-Mei WANG
1
Author Information
1. College of Life Sciences, Fujian Normal University Fujian Key Laboratory of Development and Neurobiology
- Publication Type:Journal Article
- Keywords:
glycosylation;
neuropathic pain;
phosphorylation;
T-type calcium channel 3. 2(Cav3. 2);
ubiquitination
- From:
Chinese Journal of Biochemistry and Molecular Biology
2023;39(7):1000-1007
- CountryChina
- Language:Chinese
-
Abstract:
Neuropathic pain is a common chronic pain that affects human health worldwide. As an important mediator of excitatory conduction in neurons, ion channels are important targets for mechanism research and drug research in this field. T-type calcium channel(Cav3) can be activated transiently when neurons are close to the resting potential of -70 mV, resulting in a transient Ca
