Establishment of orthotopic transplantation model of human choriocarcinoma in nude mice
10.16098/j.issn.0529-1356.2020.02.010
- Author:
Wen-Jing FAN
1
;
Yan-Jie LU
1
;
Yu-Hong LI
1
;
Lei LIU
2
;
Pin FENG
3
;
Qian XU
4
;
Yan-Zhen ZUO
5
Author Information
1. Department of Pathology, Chengde Medical University
2. Department of Immunology, Chengde Medical University
3. Department of General Surgery, 981 Hospital of Chinese PLA
4. Basic Medical Institute, Chengde Medical University
5. Department of Pharmacology, Chengde Medical University
- Publication Type:Journal Article
- Keywords:
Choriocarcinoma;
Immunohistochemistry;
JAR cell line;
Nude mice;
Xenograft
- From:
Acta Anatomica Sinica
2020;51(2):211-215
- CountryChina
- Language:Chinese
-
Abstract:
Objective Establishment of orthotopic transplantation tumor model of human choriocarcinoma in nude mice. Methods Human choriocarcinoma cell line JAR was cultured and the single cell suspension was subcutaneously injected into five 8-week-old BALB / c nude mice to establish subcutaneous xenograft model. After subcutaneous tumor was formed in nude mice, the tumor tissue was taken under aseptic conditions and cut into 1 mm
