Effect of heterotopic ossification on cervical motion following Prestige artificial cervical disc replacement
10.16098/j.issn.0529-1356.2020.03.015
- Author:
Shuai XU
1
;
Yun-Sheng OU
1
;
Xing DU
1
;
Yong ZHU
1
;
Bin HE
1
;
Yuan-Qiang LI
1
;
Hao-Yang YU
1
Author Information
1. Department ofOrthopedics, the First Affiliated Hospital of Chongqing Medical University
- Publication Type:Journal Article
- Keywords:
Clinical factor;
Heterotopic ossification;
Human;
Prestige artificial cervical disc replacement;
Range of motion;
[Key words] Cervical vertebrae
- From:
Acta Anatomica Sinica
2020;51(3):405-410
- CountryChina
- Language:Chinese
-
Abstract:
[Abstract] Objective To analyze the effect of heterotopic ossification(HO) on the postoperative segmental range of motion(ROM)after Prestige artificial cendcal disc replacement, and to explore the related factors leading to the formation of heterotopic ossification after artificial cendcal disc replacement. Methods We recruited of 66 patients who had Prestige artificial cendcal disc replacement from January 2014 to January 2018 in Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University were retrospectively reviewed. To evaluate cendcal spine X-ray, the replacement segment ROM was measured in picture, and the occurrence of HO was defined by the McAfee' s classification. The Wilcoxon signed rank test was used to analyze the relationship between heterotopic ossification formation and replacement segment ROM,the t test was used to analyze the influence between heterotopic ossification grading and replacement segment ROM. Nine clinical factors including age, gender, bod)' mass index(BMI), number of replacement segments, preoperative ligament ossification, the preoperative disc height ratio of the target level and its adjacent level, preoperative mobility of replacement segments, postoperative mobility of replacement segments, whether to use nonsteroidal autiinflammatory drugs (NSAIDs) during perioperative period. The correlation between these nine clinical factors and the occurrence of postoperative HO was evaluated with logistic regression analysis. Results The occurrence rate of HO was 34. 8% in last follow-up. The replacement segmental ROM of the heterotopic ossification group was significantly smaller than that of the non-ectopic ossification group, and the difference was statistically significant (P<0. 05),and the McAfee grade IH-IV group was significantly less than the McAfee grade I-H group, and the difference was statistically significant (P < 0. 05). Correlation analysis showed that preoperative and postoperative ROM of the replacement segment presented statistical correlation (P < 0. 05). Furthennore analysis of ROC curve showed that heterotopic ossification was more likely to occur when the degree of ROM of the replacement segment ^ 8°. Conclusion HO after Prestige artificial cervical disc replacement reduces the replacement segmental ROM,especially for the McAfee grade IH-]Vgroup.The occurrence of heterotopic ossification after Prestige artificial cervical disc replacement is related to the preoperative and postoperative mobility of the replacement segment. The ROM ^ 8 ° of the postoperative replacement segment is more likely to occur heterotopic ossification.
