Protective effect of rutin on myelin sheath injury in the sciatic nerve of rats induced by acrylamide

Author: Yan-Xian BAI ¹ ; Hui JIA ¹ ; Tong ZHANG ¹ ; Yu-You LUO ¹ ; Chun-Mei ZHANG ¹ ; Li LUO ¹ ; Yu-Xin MA ¹ ; Jing LIU ¹
Author Information

1. Department of Anatomy, College of Life Sciences and Biopharmaceuticals, Guangdong Pharmaceutical University
Publication Type:Journal Article
Keywords: Acrylamide; Immunohistochemistry; Myelin associated glycoprotein; Myelin basic protein; Rat; Rutin; Sciatic nerve; Western blotting
From: Acta Anatomica Sinica 2022;53(2):166-172
CountryChina
Language:Chinese
Abstract: [Abstract] Objective To investigate the effect of rutin (Rut) on sciatic nerve myelin injury induced by acrylamide(ACR), and to observe the changes of myelin structure, myelin basic protein (MBP) and myelin associated glycoprotein (MAG) in rats exposed to ACR. Methods Thirty-six adult male SD rats were randomly divided into 4 groups: control group (ddH