Advances in biological functions of miR-429
10.16098/j.issn.0529-1356.2022.02.019
- Author:
Jian-Lin GUO
1
;
Xue-Qing WANG
1
;
Cun-Shuan XU
1
;
Jian-Lin GUO
2
;
Xue-Qing WANG
2
;
Cun-Shuan XU
2
Author Information
1. College of Life Science, He'nan Normal University
2. State Key Laboratory Cultivation Base for Cell Differentiation Regulation, He'nan Normal University
- Publication Type:Journal Article
- Keywords:
Biological function;
Cell invasion;
Cell migration;
Cell proliferation;
MicroRNA-429
- From:
Acta Anatomica Sinica
2022;53(2):266-272
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs, miR) are endogenous non-coding single-stranded RNAs with a length of about 22 nucleotides. These RNAs play an important biological function within cells, among which, miR-429 has been proved to play an important role in inhibiting tumor development and tumor progression as well as in cell differentiation and neurological diseases by regulating the expression of different target genes. In this paper, the role of miR-429 and its downstream targeted genes in cell proliferation, apoptosis, migration and invasion is summarized.
