Effect of recombination signal binding protein for immunoglobulin Kappa J region on the proliferation and differentiation of CD133-positive ependymal cells
- Author:
Xin YE
1
;
Wei BIAN
1
;
Meng-Yi LI
1
;
An-Ting WU
1
;
Jun-Wei LI
1
;
Peng ZHOU
1
;
Huai-Rui CUI
1
;
Chen-You SUN
1
;
Xin YE
2
;
Wei BIAN
2
;
Meng-Yi LI
2
;
An-Ting WU
2
;
Jun-Wei LI
2
;
Peng ZHOU
2
;
Chen-You SUN
2
;
Ting ZHANG
3
Author Information
- Publication Type:Journal Article
- Keywords: CD133-positive ependymal cell; Immunofluorescentce; Mouse; Notch signaling pathway; Recombination signal binding protein for immunoglobulin Kappa J region
- From: Acta Anatomica Sinica 2022;53(2):144-154
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the effect of recombination signal binding protein for immunoglobulin Kappa J region (RBP-Jκ) on the proliferation and differentiation of CD133￣positive ependymal cells and its possible mechanism. Methods RBP-Jκ in CD133-positive ependymal cells of lateral ventricle was interfered with siRNA in the fetuses of embryos which were isolated from 12-day pregnant Institute of Cancer Research(ICR) mouse (3 mice) and knocked out in CD133-CreER
