Progress in drug prevention and treatment of migraine
10.12092/j.issn.1009-2501.2020.12.016
- Author:
Xinyi YANG
1
;
Jing ZHANG
1
;
Nanyang LI
1
;
Haijing YANG
1
;
Xiaomeng MAO
1
Author Information
1. Phase I Unit, Huashan Hospital, Fudan University
- Publication Type:Journal Article
- Keywords:
Migraine;
Monoclonal antibody against CGRP;
Pharmacokinetics
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(12):1429-1435
- CountryChina
- Language:Chinese
-
Abstract:
Migraine is a common nervous system disease, which could seriously affect the quality of life. However, the medical treatment of migraine cannot meet the clinical needs at present. With the deepening of research, serotonin 1F receptor agonists and drugs targeting CGRP are more and more developed and marketed. In this paper, the mechanism of action, safety and efficacy, metabolic characteristics of these drugs were systematically evaluated to provide a more scientific basis for clinical prevention and treatment of migraine.