Comparison of the calculation approaches of AUC in non-compartment model pharmacokinetics
10.12092/j.issn.1009-2501.2020.12.010
- Author:
Chao CHEN
1
;
Xue LI
1
;
Qingshan ZHENG
2
;
Lujin LI
2
;
Ling XU
2
Author Information
1. National Drug Clinical Trial Institution of Longhua Hospital Shanghai University of Traditional Chinese Medicine
2. Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Area under the plasma concentration-time curve (AUC);
Bioequivalence;
Pharmacokinetics
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(12):1381-1387
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the ways of calculating area under the plasma concentration-time curve (AUC) in non-compartment model pharmacokinetics by comparing the accuracy & precision of every method. METHODS: Three methods were used to calculate the area under 0-T curve (AUC
