AHVAC-I reverses tumor growth of cancer-associated fibroblasats in gastric cancer
- Author:
Yuhua JIANG
1
;
Hui ZHI
1
;
Linming LU
1
;
Dahao TIAN
1
;
Xiaoqing WANG
1
;
Yu GE
1
;
Shangfu XIE
1
;
Qi WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Agkistrodon halys venom antitumor component-I; Chemokine CXCL12; Gastric cancer cell migration; Gastric cancer-associated fibroblast
- From: Chinese Journal of Clinical Pharmacology and Therapeutics 2021;26(4):389-394
- CountryChina
- Language:Chinese
- Abstract: AIM: To explore whether Agkistrodon Halys venom antitumor component-I (AHVAC-I) affects the migration of gastric cancer cells by human primary gastric cancer-associated fibroblast (GCAFs). METHODS: Tissue block culture and trypsin digestion were used to separate and culture human primary gastric cancer-associated fibroblasts (GCAFs); the GCAFs-CM
