Protective effects of the extract from Toona sinensis seeds on gastric mucosa injury in experimental mice
10.12092/j.issn.1009-2501.2021.05.011
- Author:
Lihua LI
1
;
Shengpeng ZHANG
1
;
Jiaxu QIN
1
;
Sihui NIAN
1
Author Information
1. School of Pharmacy, Wannan Medical College
- Publication Type:Journal Article
- Keywords:
Aspirin;
Ethanol;
Gastric mucosa injury;
Protective effect;
The extract of Toona sinensis seeds
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2021;26(5):546-551
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study protective effects of the extract from Toona sinensis seeds on gastric mucosal injury in experimental mice. METHODS: The mice were given 200 mg/kg, 400 mg/kg of Toona sinensis seeds every day for 2 weeks and ethanol or aspirin was used to induce gastric mucosa injury model. The gastric mucosal injury index and injury inhibition rate were calculated, the levels of SOD, MDA in serum and the contents of ET-1, PGE
