Progresses in clinical manifestations and treatments of narcolepsy
10.12092/j.issn.1009-2501.2021.05.003
- Author:
Mengmeng WANG
1
;
Zhongxin ZHAO
1
;
Huijuan WU
1
;
Mengmeng WANG
2
Author Information
1. Department of Neurology, Changzheng Hospital, Naval Medical University
2. Department of Hyperbaric Oxygen and Neurology, Naval Special Medical Center
- Publication Type:Journal Article
- Keywords:
Cataplexy;
Excessive daytime sleepiness;
Narcolepsy;
Treatment
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2021;26(5):491-496
- CountryChina
- Language:Chinese
-
Abstract:
Narcolepsy is a rare disease that presents with sleep-wake disorder, which divided into narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). NT1 accounts for more than 75%, which is characterized by excessive daytime sleepiness (EDS), cataplexy attacks and nocturnal sleep symptoms (e.g. sleep paralysis, hallucinations, sleep disruptions, sleep movement disorders, etc.), accompanied by metabolic, psychiatric and emotional disturbances. The main clinical manifestation of NT2 is EDS, without cataplexy and nonspecific other symptoms of NT1. The treatments of narcolepsy mainly include the treatments of EDS and cataplexy, as well as the improvement of nocturnal sleep. This article will elaborate the advances in clinical manifestations and treatments of narcolepsy.
