Research progress of relevance between cholecystokinin and depression
10.12092/j.issn.1009-2501.2021.06.010
- Author:
Yeqing WANG
1
;
Yuhong WANG
1
;
Hongqing ZHAO
1
;
Manshu ZOU
1
;
Jian LIU
2
Author Information
1. Institute of Innovation and Applied Research, Hunan University of Chinese Medicine
2. The First Affiliated Hospital of Hunan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Cholecystokinin;
Depression;
Mechanism;
Neurons
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2021;26(6):672-679
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a mental illness characterized by significant and lasting depression. Recent studies have found that cholecystokinin, as a small brain-gut peptide molecule, is widely distributed in the central nervous system and enteric nervous system. In order to further clarify the relationship between CCK and the pathogenesis of depression, this article reviews the effect of CCK in depression, including HPA axis, synaptic function and circuit mechanism, etc.
