Research progress of glutamine metabolism in liver cancer
10.12092/j.issn.1009-2501.2021.10.008
- Author:
Zhuo LIU
1
;
Xiaoning TAN
1
;
Puhua ZENG
1
Author Information
1. Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Glutamine metabolism;
Liver cancer;
Mechanism
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2021;26(10):1159-1166
- CountryChina
- Language:Chinese
-
Abstract:
Liver cancer is one of the most dangerous malignant tumors in China. It has the characteristics of high mortality and occult onset. At present, the treatment of liver cancer is mainly targeted drugs, surgery and chemoradiotherapy, which is prone to high recurrence rate and strong drug resistance. In this paper, glutamine metabolism as the breakthrough point, the glutamine metabolism enzymes and related genes related to liver cancer are reviewed, in order to provide an open new idea for the pathogenesis and drug treatment of liver cancer.
