Research progress on ferroptosis regulators and their role in stroke

Author: Hailin ZHANG ¹ ; Yong CHEN ¹ ; Chao LU ¹ ; Wei HU ¹ ; Renpeng ZHOU ¹ ; Hailin ZHANG ² ; Yongfeng BA ²
Author Information

1. Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University
2. School of Pharmacy, Anhui Medical University
Publication Type:Journal Article
Keywords: Ferroptosis; Free Fe; Lipid peroxide; Regulator; Stroke
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2021;26(11):1320-1327
CountryChina
Language:Chinese
Abstract: Stroke is a brain injury caused by sudden rupture or blockage of blood vessels in the brain, with different types and varying degrees death in cellular level. And there is currently no effective treatment for it. Ferroptosis is a new type of cell death discovered in recent years that is related to factors such as lipid peroxides, reactive oxygen species (ROS), and Fe