Advances in evidence-based medical research of GnRHa for fertility protection after chemotherapy
10.12092/j.issn.1009-2501.2021.12.017
- Author:
Quanfeng ZHAO
1
;
Peishu FU
1
;
Wenrui GU
1
;
Dan ZHEN
2
;
Zongjie LV
2
;
Yang YANG
2
Author Information
1. Department of Pharmacy, Southwest Hospital, First Affiliated Hospital to Third Military Medical University (Army Medical University)
2. Department of Pharmacy, Chongqing Health Center for Women and Children
- Publication Type:Journal Article
- Keywords:
Chemotherapy;
Evidence-based medicine;
Fertility protection;
Gonadotropin-releasing hormone agonists (GnRHa)
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2021;26(12):1449-1454
- CountryChina
- Language:Chinese
-
Abstract:
With an improvement in the long-term survival rates of cancer patients, the requirements for fertility protection of young cancer patients after chemotherapy are increasingly prominent. Early studies have shown that gonadotropin-releasing hormone agonist (GnRHa) has a protective effect on fertility. But in recenct year, relevant studies have shown that its protective effect is controversial. This article reviews the clinical researches of GnRHa for fertility protection in patients with common tumors, and explores its evidence-based medicine, in the hope of providing references for reasonable clinical application.
