Association of Lin28 with tumor, cardiovascular disease and diabetes
10.12092/j.issn.1009-2501.2022.02.012
- Author:
Xiaohan LV
1
;
Xiaohan LV
2
;
Rong LIN
2
Author Information
1. Department of Pharmacy, Xi'an No.3 Hospital, The Affiliated Hospital of North West University
2. Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center
- Publication Type:Journal Article
- Keywords:
Cardiovascular;
Diabetes;
Disease;
Lin28;
Tumor
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2022;27(2):205-211
- CountryChina
- Language:Chinese
-
Abstract:
Lin28 is a highly conserved RNA-binding protein, including Lin28a and Lin28b. Lin28 is involved in many physiological processes such as cell differentiation, growth and metabolism. In recent years, it has been found that Lin28 is closely related to the pathogenesis and development of numerous major diseases. The relationships between Lin28 and related diseases such as tumor, cardiovascular disease and diabetes are reviewed in this article.