Research progress on bone metabolism disorders associated with PCOS elucidated from endocrine hormones
10.12092/j.issn.1009-2501.2022.03.013
- Author:
Chen DU
1
;
Yang CAO
1
;
Chen DU
2
;
Yongjun WANG
2
;
Yan ZHANG
2
;
He TIAN
3
Author Information
1. Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
2. Longhua Hospital, Shanghai University of Traditional Chinese Medicine
3. Shenzhen Pingle Orthopaedic Hospital
- Publication Type:Journal Article
- Keywords:
Bone metabolism;
Endocrine;
Hormone;
Osteoporosis;
Polycystic ovary syndrome
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2022;27(3):328-333
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is a common endocrine metabolic disease of women. Clinical studies have shown that PCOS patients are likely having abnormal bone metabolism, and with increased risk of osteoporosis. This review summarized the common pathological mechanisms for both PCOS and osteoporosis, and elucidated the research progress on PCOS-inducing bone metabolism disorders from emphasizing on the regulation of endocrine hormones including insulin, androgen, growth hormone, vitamin D, parathyroid hormone and calcitonin. It is expected that this review will shed new light on monitoring and intervention for bon health of PCOS patients.