Research progress on interaction between tumor microenvironment and breast cancer cells leading to tumor metastasis
10.12092/j.issn.1009-2501.2022.05.010
- Author:
Jingbin SHI
1
;
Yang XIONG
1
;
Jingbin SHI
2
;
Yang XIONG
2
Author Information
1. School of Pharmaceutical Science, Zhejiang Chinese Medical University
2. Academy of Chinese Medical Science, Zhejiang Chinese Medical University
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Invasion;
Metastasis;
Preventive treatment;
Tumor microenvironment
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2022;27(5):562-574
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a malignant tumor with strong invasiveness, strong metastasis and high recurrence rate. Breast cancer cells can be transferred to different tissues in a variety of ways. Breast cancer cells can spread because of the tumor microenvironment created by tumor interaction with surrounding cells. This review examines the role and mechanisms of the tumor microenvironment in breast cancer cell metastasis in recent years, including adipocytes, fibroblasts, neuroendocrine cells, immune and inflammatory cells, blood and lymphatic network, and extracellular matrix, as well as how to treat breast cancer metastasis.
