Protease Activities in Various Kinds of Enzymatic Cleaners for Contact Lenses.
- Author:
Jae Ho KIM
1
;
Hiroshi TANOUCHI
Author Information
1. Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University, Medical College, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Contact Lenses*;
Contact Lenses, Hydrophilic
- From:Journal of the Korean Ophthalmological Society
1988;29(1):69-75
- CountryRepublic of Korea
- Language:English
-
Abstract:
UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effctive for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high proteasea activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10 ~ 30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.