Research progress on the role and mechanism of irisin in organ ischemia/ reperfusion injury

Author: Xiaoxia HAN ¹ ; Yufang LENG ¹ ; Xingjiao LV ¹ ; Xiaoyu HOU ¹ ; Xuefen CAO ¹ ; Janvier NIBARUTA ¹ ; Yufang LENG ²
Author Information

1. First Medical College of Lanzhou University
2. Department of Anesthesiology, First Hospital of Lanzhou University
Publication Type:Journal Article
Keywords: function; irisin; mechanism; organ ischemia/reperfusion
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2022;27(8):886-891
CountryChina
Language:Chinese
Abstract: lrisin is an endogenous secreted muscle factor, Which not only plays a certain clinical application value in a variety of metabolic diseases, cardiovascular and cerebrovascular diseases, neurological diseases, tumors and other diseases, but also affects the occurrence and development of organ ischemia/reperfusion injury. ln this paper, the role and mechanism of irisin in organ ischemia/reperfusion injury Were summarized, aiming to provide neW ideas for prevention and treatment of organ ischemia/reperfusion injury.