The mechanism of Shugan Jianpi Formula regulating TLR4/MyD88/NLRP3 signaling axis to inhibit pyroptosis in mice with liver fibrosis
- Author:
Sen CHEN
1
;
Chang FAN
1
;
Jiafu ZHANG
1
;
Yanzhen MA
1
;
Hui JIANG
1
Author Information
- Publication Type:Journal Article
- Keywords: liver fibrosis; pyroptosis; Shugan Jianpi Formula; TLR4/MyD88/NLRP3 signaling axis
- From: Chinese Journal of Clinical Pharmacology and Therapeutics 2022;27(10):1081-1089
- CountryChina
- Language:Chinese
- Abstract: AIM: To explore the therapeutic effect and mechanism of Shugan Jianpi Formula on liver fibrosis mice based on TLR4/MyD88/NLRP3 signaling axis. METHODS: The chemical liver fibrosis mouse model was established by carbon tetrachloride (CCl
