Effects of different doses of dexmedetomidine on non-cardiac surgery stress and postoperative sleep in patients with coronary heart disease
10.12092/j.issn.1009-2501.2022.12.003
- Author:
Lei YAN
1
;
Haibin JIANG
1
;
Paerhati NAFEISHA
1
;
Yikemu REZIWANGULI
1
;
Boyu GENG
1
;
Maimaitiaili MAIERHABA
1
Author Information
1. Department of Anesthesiology, People's Hospital of Xinjiang Uygur Autonomous Region
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
dexmedetomidine;
hemodynamics;
non-cardiac surgery;
postoperative sleep
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2022;27(12):1340-1346
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effects of different doses of degmedetomidine on stress and postoperative sleep in patients with coronare heart disease (CHD). METHODS: Sigte patients with coronare heart disease undergoing endoscopic abdominal surgere were randomle divided into three groups (n d 20): low-dose group (D1), high-dose degmedetomidine group (D2) and control group (C) In groups D1 and D2, a loading dose of degmedetomidine (0.5 μg/kg) was injected with intravenous pump for 10 min, followed be the maintain dose of degmedetomidine 0.2 and 0.6 μg·kg