Clinical efficacy and anti-inflammation/anti-fibrosis effect of tripterygium glycosides in the treatment of diabetic nephropathy

Author: Yiqi XU ¹ ; Qian WU ¹ ; Shu LIU ¹ ; Fan LIU ¹ ; Chunyan XING ¹ ; Qin LI ¹ ; Junjun HE ¹ ; Chunling HE ¹ ; Yongli ZHAO ¹ ; Jialin GAO ¹ ; Jialin GAO ² ; Jialin GAO ³
Author Information

1. Department of Endocrinology, Yijishan Hospital, Wanan Medical College
2. Diabetic Nephropathy Clinical Diagnosis and Research Center (Wuhu) of Anhui Province
3. Diabetic Nephropathy Research Laboratory of Wannan Medical College
Publication Type:Journal Article
Keywords: clinical efficacy; diabetic kidney disease; diabetic mellitus; tripterygium glycosides
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2023;28(9):1034-1042
CountryChina
Language:Chinese
Abstract: AIM: To observe the clinical efficacy of multi -glycoside of tripterygium wilfordii (GTW) on diabetic nephropathy. METHODS: Fifty-one patients with diabetic kidney disease (DKD) with a history of GTW dosing admitted to the outpatient clinic of Yijishan Hospital affiliated to Wannan Medical College from June 2019 to October 2022 were selected as study subjects, and were followed up regularly to observe the changes in laboratory indexes before and after GTW dosing and adverse drug reactions after 6 months of treatment. The t-test, Mann-Whitney U-test or χ