Effects of esketamine combined with sufentanil on postoperative analgesia and emotion after thoracoscopic radical resection of lung cancer
10.12092/j.issn.1009-2501.2023.01.008
- Author:
Yang SU
1
;
Feng ZHOU
1
;
Jinlei DING
1
Author Information
1. Department of Anesthesiology, Second Affiliated Hospital of Dalian Medical University
- Publication Type:Journal Article
- Keywords:
emotion;
esketamine;
lung cancer;
patient-controlled intravenous analgesia;
thoracoscopy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2023;28(1):59-65
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the effect of Esketamine combined with sufentanil on analgesia and emotion after thoracoscopic radical resection of lung cancer. METHODS: A total of 108 patients undergoing thoracoscopic radical resection of lung cancer were randomly divided into three groups: Esketamine plus sufentanil patient-controlled analgesia group (S group), low-dose sufentanil patient-controlled analgesia group (LC group) and high-dose sufentanil patient-controlled analgesia group (HC group). PCIA was performed after operation. The formula of analgesia pump in group S: Esketamine 1.2 mg/kg, sufentanil 1 μg/kg, LC group analgesic pump formula: sufentanil 1 μg/kg; Formula of analgesic pump in HC group: sufentanil 1.5 μg/kg; Tropisetron 10 mg was added to three groups of analgesia pumps, and normal saline was diluted to 100 mL. Observe the visual analogue scale (VAS) and Ramsay sedation score of resting and exercise pain at 6 h (T
