Progress on the pathological mechanism and treatment of frostbite
10.12092/j.issn.1009-2501.2023.03.014
- Author:
Li ZHANG
1
;
Xingyao LIN
1
;
Yun SHANG
1
;
Qiang WANG
1
;
Xingyao LIN
2
Author Information
1. Gansu University of TCM
2. The Key Laboratory of the Ministry of Education of Dunhuang Medicine and Transformation
- Publication Type:Journal Article
- Keywords:
frostbite;
pathological mechanism;
research progress;
treatment
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2023;28(3):347-354
- CountryChina
- Language:Chinese
-
Abstract:
Frostbite is a tissue injury that occurs when the body is exposed to extreme cold. Its pathological mechanism is complex and has not been fully elucidated. In high cold and high altitude areas, outdoor sports people have a high risk of injury, and severe frostbite has high disability and mortality. Exploring the pathological mechanism of frostbite is helpful to determine the treatment methods and timing. At present, the clinical treatment of frostbite is mainly symptomatic treatment, such as drug treatment and surgical treatment, but the curative effect can not meet the clinical needs. Therefore, it is of great significance to seek more efficient drugs or treatment methods. This article reviews the relevant research progress in pathophysiological mechanism, clinical treatment, cellular and molecular pathways of frostbite in recent years, in order to provide new ideas for future research and clinical treatment.
