Effects and mechanism of traditional Chinese medicine injection in prevention and treatment of cardiotoxicity induced by antineoplastic drugs
10.12092/j.issn.1009-2501.2023.05.012
- Author:
Yanyang LI
1
;
Yanyang LI
2
;
Yanyang LI
3
;
Yanyang LI
4
;
Yunjiao WANG
5
;
Shichao LV
5
Author Information
1. Department of Integrated Traditional & Western Medicine, Tianjin Medical University Cancer Institute and Hospital
2. National Clinical Research Center for Cancer
3. Key Laboratory of Cancer Prevention and Therapy
4. Tianjin's Clinical Research Center for Cancer
5. Department of Geratology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
cardiotoxicity;
malignant tumor;
oncocardiology;
traditional Chinese medicine injection
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2023;28(5):572-577
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine injections for the prevention and treatment of cardiotoxicity of antineoplastic drugs was summarized, including Shengmai injection, Shenmai injection, Shenfu injection, Shenqi Fuzheng injection, Kangai injection, Huangqi injection, Xinmailong injection, Danhong injection, Danshen injection, Honghua injection, Kushen injection, Cinobufacin injection and Yinxingdamo injection. The mechanism of effect mainly includes inhibition of lipid peroxidation, reduction of calcium overload and anti-cardiomyocyte apoptosis, which provides the basis for the prevention and treatment of cardiotoxicity of antitumor drugs by traditional Chinese medicine.
