Research progress on the relationship between subclinical hypothyroidism and depression
10.12092/j.issn.1009-2501.2023.08.012
- Author:
Taotao ZHANG
1
;
Limin TIAN
1
;
Wenxiu SU
2
;
Limin TIAN
2
;
Limin TIAN
3
Author Information
1. The First Clinical Medical College, Lanzhou University
2. Department of Endocrinology, Gansu Provincial Hospital
3. Gansu Clinical Research Center For Metabolic Diseases
- Publication Type:Journal Article
- Keywords:
depression;
levothyroxine;
relationship;
subclinical hypothyroidism
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2023;28(8):954-960
- CountryChina
- Language:Chinese
-
Abstract:
Subclinical hypothyroidism (SCH) is a mild impairment of thyroid function. Several existing studies suggest that SCH is associated with an increased risk of depression, but some studies have also found no correlation between SCH and depression. Therefore, whether there is an association between SCH and depression and the mechanism of interaction between the two remains controversial. Growing evidence suggested that SCH patients should not be routinely treated with levothyroxine, and the effect of the treatment of thyroid disease on various clinical psychiatric outcomes is also controversial. This article reviews the current research on the correlation between SCH and depression risk and whether drug intervention is needed.
