A bioequivalence study of generic and brand clozapine in schizophrenic patients
- Author:
Xuejing LI
1
;
Jinping JIANG
1
;
Sining LI
1
;
Linfei WAN
1
;
Xiangxiang ZHOU
1
;
Lian YANG
1
;
Ke LAN
1
;
Xuejing LI
2
;
Lian YANG
2
;
Ke LAN
2
;
Ke LAN
3
Author Information
- Publication Type:Journal Article
- Keywords: bioequivalence; clozapine; pharmacokinetics; steady-state; UPLC-MS/MS
- From: Chinese Journal of Clinical Pharmacology and Therapeutics 2023;28(10):1121-1130
- CountryChina
- Language:Chinese
- Abstract: AIM: To establish a ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to determination the plasma concentration of clozapine and compare the bioequivalence of a generic clozapine tablet with Clozaril
