Mechanism of Pingxiao capsule promoting breast cancer apoptosis through AKT1/β-catenin signal based on network pharmacology

Author: Hongxiao CHEN ¹ ; Zhaolin CHEN ¹ ; Hongxiao CHEN ² ; Su LIU ² ; Le JIN ² ; Lei ZHANG ² ; Zhaolin CHEN ² ; Huihui ZHANG ³
Author Information

1. School of Pharmacy Anhui Medical University
2. The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
3. Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine
Publication Type:Journal Article
Keywords: AKT1/β-catenin; breast cancer; molecular docking; network pharmacology; Pingxiao capsule
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2023;28(12):1321-1330
CountryChina
Language:Chinese
Abstract: AIM: To explore the potential mechanism of action of Pingxiao capsule in the treatment of breast cancer. METHODS: TCMSP, TCM-ID, GeneCards and other databases were used to screen the related targets of Pingxiao capsule and breast can-