Research progress on molecular mechanism of traditional chinese medicine active ingredients interfering bone marrow mesenchymal stem cells senescence
10.12092/j.issn.1009-2501.2024.01.011
- Author:
Miaoying YU
1
;
Yanhui WANG
2
;
Shi YAN
3
Author Information
1. College of Life Science, Shangrao Normal University
2. School of basic medicine, Jiangxi Medical College
3. Health-Biotech Group, Jiangxi H&B Stem Cell Technology Limited Company
- Publication Type:Journal Article
- Keywords:
bone marrow mesenchymal stem cells;
molecular mechanism;
senescence;
traditional chinese medicine active ingredient
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(1):99-106
- CountryChina
- Language:Chinese
-
Abstract:
The senescence of bone marrow mesenchymal stem cells (BM-MSCs) will induce age-related bone tissue degeneration and chronic inflammation, and reduce its application effect for cell therapy. More and more active ingredients of traditional chinese medicine have been proved to intervene BM - MSCs senescence, playing an important role in bone diseases prevention and treatment, and improving the therapeutic effect of BM-MSCs. In this paper, the latest research progress on the molecular mechanism of traditional chinese medicine active ingredients interfering BM-MSCs senescence was summarized, in order to provide new direction and reference basis for senescence intervention research and clinical application improvement of BM-MSCs.
