Di'ao Xinxuekang activates IRS-1/PI3K/Akt signal pathway to improve insulin resistance in nonalcoholic fatty hepatitis mice
10.12092/j.issn.1009-2501.2024.02.001
- Author:
Xin WANG
1
;
Muhong SHANG
1
;
Yuyan LIU
1
;
Guangliang CHEN
1
;
Yifan WANG
2
Author Information
1. College of Integrated Medicine, Anhui University of Chinese Medicine
2. School of Medical Economics and Management, Anhui University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Di'ao Xinxuekang;
insulin resistance;
IRS-1/PI3K/Akt signaling pathway;
non alcoholic steatohepatitis
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(2):121-129
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect and mechanism of Di'ao Xinxuekang (DXXK) on insulin resistance in nonalcoholic steatohepatitis (NASH) mice. METHODS: C57BL/6J mice were randomly divided into normal group and model group. After 16 weeks of high-fat diet, the model group was randomly divided into model group and Pioglitazone group (6.0 mg · kg
