Use of central neuromodulators in chronic cough
10.12092/j.issn.1009-2501.2024.04.011
- Author:
Bingxian SHA
1
;
Haodong BAI
1
;
Wanzhen LI
1
;
Li YU
1
;
Xianghuai XU
1
Author Information
1. Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University
- Publication Type:Journal Article
- Keywords:
chronic cough;
cough hypersensitivity syndrome;
neuromodulator
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(4):432-439
- CountryChina
- Language:Chinese
-
Abstract:
Chronic cough is a common condition that imposes significant physical, psychological, and social burdens on patients. Although chronic cough is often associated with underlying conditions such as asthma, gastroesophageal reflux disease, and eosinophilic bronchitis, some patients experience uncontrollable coughing that is difficult to attribute to a specific cause. Many of these patients exhibit clinical features of cough hypersensitivity syndrome, providing new directions for research into the treatment of chronic cough. As the pathophysiological mechanisms of chronic cough are further elucidated, treatment approaches for chronic cough are entering a new stage of development. This article summarizes and discusses the mechanisms and clinical evidence of central neuromodulators used in the treatment of chronic cough, suggesting promising clinical applications for these drugs in the future.
