Targeted biotherapy for chronic obstructive pulmonary disease
10.12092/j.issn.1009-2501.2024.04.003
- Author:
Haodong BAI
1
;
Bingxian SHA
1
;
Ambedkar Kumar YADAV
1
;
Xianghuai XU
1
;
Li YU
1
Author Information
1. Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease;
cytokine;
targeted therapy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(4):377-382
- CountryChina
- Language:Chinese
-
Abstract:
Chronic obstructive pulmonary disease (COPD) is the most common chronic airway disease. The current status of treatment based mainly on bronchodilators and ICS is not sufficient for all of COPD patients. Various studies have attempted to use biologics targeting specific cytokines and their receptors in COPD patients to alleviate respiratory symptoms or reduce the risk of acute exacerbations. However, they failed to bring significant clinical benefits. More studies are needed to further determine the efficacy of targeted biotherapy for COPD.
